Join us

Open projects

The CoWaS project tackles the challenge of biodiversity monitoring in water bodies. To achieve a solution for autonomous analysis, we work on the following topics:

1. Microneedles Patch
1-2 Students
Available positions
0%

To optimize the current design of the Microneedles patch, the materials choice and fabrication process need to be refined. This process must be supported by regular tests to assess the performance in extracting DNA. The degradation of the patches in different storage conditions must also be evaluated.

Keywords: Materials, Fabrication process, Hydrogels, Prototyping and Testing

2. User interface
2-3 Students
Available positions
0%

The aim is to design a device that will enable easy handling of the microneedles patch by the operator during the sampling and will protect the patch from contaminations before and after the sampling.

Keywords: Mechanical design, Prototyping, Ergonomics, Sampling

3. DNA Extraction
1-2 Students
Available positions
0%

To further enhance the performances of the Microneedles, improvements in the DNA extraction process must be investigated. These improvements include the choice and application method of the Elution buffer and the addition of a purification step before amplification.

Keywords: Life sciences, Biochemistry, DNA extraction, DNA purification

The CoWaS project tackles the challenge of biodiversity monitoring in water bodies. To achieve a solution for autonomous analysis, we work on the following topics:

1. Water Sampling
2-3 Students
Available positions
0%

The aim is to develop a water pumping and filtration system that can be pre-programmed or remotely controlled to ensure an operator-free continuous sampling of a water body at a fixed depth.

Keywords: Water sampling, Mechanical/Electrical Design, Programming, Communication system, Environmental sampling

2. DNA Extraction
2-3 Students
Available positions
0%

The water samples must then be processed to extract the DNA contained in them. A suitable extraction pipeline must be designed based on the first tests and results that have already been carried out.

Keywords: DNA extraction, Biochemistry, Environmental & Life sciences

3. Microfluidics and Miniaturization
2-3 Students
Available positions
0%

A continuous monitoring places constraints on the design of the instrument implementing the DNA extraction pipeline. It must be automated and miniaturized to enable its effective use in the field.

Keywords: Automation, Robotics, Materials, Microfabrication, Microfluidics

The DNA Sensor team works on the development of an integrated DNA quantification sensor. It will be integrated to the instrument to assess the quality of the DNA extraction before sequencing. This implies challenging design constraints to ensure the sensor’s integrability, accuracy and reliability. The following topics are available:

1. Proof of Concept
1-2 Students
Available positions
0%

A first Proof of Concept based on UV absorption is currently being developed and tested assess its performances.

Keywords: Design & Prototyping, Optics, Electronics, DNA quantification

2. Miniaturization and Integration
1-2 Students
Available positions
0%

The current design is a small table-top instrument. The concept should be adapted to an integrated and microfabricated sensor that can interface with a microfluidic system.

Keywords: Microfabrication, Design, Optics, DNA quantification

The focus here is the development of the biodiversity database with its associated software tools and hardware equipment. It will store the data produced during survey and monitoring expeditions and will propose a set of bioinformatics and analysis tools. We are currently working on the following topics:

1. User interface tools
1-2 Students
Available positions
0%

The aim is to develop software tools (desktop and/or web-based) to enable user-friendly actions such as data upload/download.

Keywords: Software development, User interface, Database

2. Interfacing with international Biodiversity Databases
1-2 Students
Available positions
0%

The current version of the database is not currently linked to standard international Databases such as GenBank. The goal is to design an interface that enables data exchange between these systems. 

Keywords: Database management, Data structure, Interfaces

3. Field equipment
2-3 Students
Available positions
0%

The data will be generated mostly during expeditions in harsh environment. It needs to be stored locally until it can be uploaded to the main database. This part of the project focuses on the development of a solution for storing and exchanging data with the database during field expeditions.

Keywords: Field hardware, Data storage, Communication system, Electrical/Mechanical Design, Prototyping

We are always looking for interested and motivated students to join the GenoRobotics student association. You can get involved in various roles such as:

 

  • communication
  • website administration
  • sponsoring
  • recruiting
  • project management

The GenoRobotics project tackles the challenge of field sequencing. To achieve a solution for autonomous on-site analysis, we work on the following topics:

Nanopore DNA Sequencing
2 Students
Available positions
0%

Using genomic DNA, the aim is to work on library preparation to sequence four genes with the use of a Nanopore sequencer.

Keywords: MinION, Nanopore sequencing, Laboratory work, Biology, genomic DNA , Environmental & Life sciences

2. Isothermal amplification
2 Student
Available positions
0%

After DNA extraction, DNA has to be amplified to prepare library for Nanopore sequencing. A isothermal amplification pipeline must be designed in order to develop a field compatible tool.

Keywords: DNA extraction, DNA amplification, Biology, Biochemistry, Environmental & Life sciences

3. Plant DNA Sequencing
2 Students
Available positions
0%

In collaboration with project 1, the goal is to extract with microneedles, DNA from plant leaves in order to sequence the four primers with a Nanopore sequencer.

Keywords: MinION, Nanopore sequencing, , Biology, Plant DNA barcoding, Environmental & Life sciences

If you didn’t find a suitable project listed but are still interested in joining GenoRobotics, you are most welcome to contact us!
We will do our very best to work something out.

Want to join the adventure?